1상모집 중단 (진행 중)

AZD9291 in Combination With Ascending Doses of Novel Therapeutics

연구 개요

The purpose of this study is to determine the safety, tolerability and preliminary anti-tumour activity of AZD9291 when given together with AZD6094 or selumetinib in patients with EGFR mutation positive advanced lung cancer

스폰서: 리드: 아스트라제네카
적응증: Advanced Non Small Cell Lung Cancer
중재: Part A - AZD9291 in combination with AZD6094, Part A - AZD9291 in combination with continuous selumetinib (Asian subjects), Part A - AZD9291 in combination with continuous selumetinib (non-Asian subjects), Part A - AZD9291 in combination with intermittent selumetinib, Part A - AZD9291 in combination with MEDI4736, Part B - AZD9291 in combination with AZD6094, Part B - AZD9291 in combination with selumetinib, Part B - AZD9291 in combination with MEDI4736, Part C - AZD6094 monotherapy (Japan only), Part C - AZD9291 in combination with AZD6094 (Japan only), Part D - AZD9291 in combination with AZD6094
목표 등록: 344명
시작일: 2014-08-05
완료(예정): 2026-12-31
등록번호: NCT02143466 · ClinicalTrials.gov ↗

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