1상모집 중단 (진행 중)
Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer
연구 개요
Phase 1 study for patients with resected PDAC after neoadjuvant and/ or adjuvant chemotherapy and/or radiation, as well as patients with metastatic colorectal cancer who have exposure to 2 or more lines of chemotherapy, to evaluate safety and the immune response to pooled mutant-KRAS peptide vaccine (KRAS peptide vaccine) with poly-ICLC adjuvant in combination with nivolumab and ipilimumab.
- 스폰서
- 협력: BMS
- 적응증
- Colorectal Cancer, Pancreatic Cancer
- 중재
- KRAS peptide vaccine, Nivolumab, Ipilimumab
- 목표 등록
- 27명
- 시작일
- 2020-05-28
- 완료(예정)
- 2027-06-01
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