백신
성숙
감염병·암을 예방·치료하는 백신. mRNA 등 새 플랫폼으로 개발 속도가 빨라졌다.
전망 개인 맞춤형·치료용 백신과 범용(broad) 백신으로 영역 확장.
개발 기업
관련 뉴스
전체 →최신 연구
전체 →NPJ vaccines
mRNA 암 백신의 단일세포 기술Science advances
지질 나노입자 기반 mRNA 백신에서 별개의 항원 제시 경로가 강력한 T 세포 면역을 유도한다bioRxiv (프리프린트)
Subunit vaccination enhances protection conferred by prior Mycobacterium tuberculosis exposurebioRxiv (프리프린트)
What Do Generative Models Learn About Adaptive Immune Receptor Repertoires? A Benchmark StudyProceedings of the National Academy of Sciences of the United States of America
IVT-free, chemically synthesized protein-encoding RNA oligonucleotides for rapid production of personalized cancer vaccinesbioRxiv (프리프린트)
High-Density Wild-Type IL-2 Nanoparticles Preferentially Enhance CD8⁺ T-Cell Expansion and Reprogram the Tumor MicroenvironmentbioRxiv (프리프린트)
Systemic-to-mucosal trafficking of memory B cells contributes to humoral immunity in the upper respiratory tractbioRxiv (프리프린트)
Analysis of SIV Spatiotemporal Dissemination Patterns in Rhesus Macaques During Early Rectal Transmission Demonstrates Systemic Infection Does Not Require Viral Local Amplification at the Entry PortalbioRxiv (프리프린트)
Oral Administration of Hyperimmune Eggs Induces Mucosal IgA Responses, Anti-Idiotypic Antibodies, and HIV-1 Neutralizing Activity: A Proof-of-Concept Preclinical StudybioRxiv (프리프린트)
replicateFest: An R Package and Shiny App for Analysis of T Cell Receptor Repertoire Data from the Functional ExpansionbioRxiv (프리프린트)
Learned Immune Architectures of Durable Antibody Responses Across VaccinesbioRxiv (프리프린트)
Computational design of structurally diverse antibody repertoires with drug-like properties
진행 중 임상
전체 →- 1상모집 예정3회 기본 투여 후 12~15개월에 부스터 투여를 받는 영아의 시험용 폐렴구균 백신의 안전성 및 반응원성 평가 시험
- 2상모집 예정건강한 지원자에서 인마젭 투여와 에르베보 백신 접종 사이의 시간 간격이 백신 면역반응에 미치는 영향
- 단계 미표기모집 예정Post-marketing Surveillance Study for the Safety of Efluelda® Pre-filled Syringe
- 단계 미표기모집 예정Post-marketing Surveillance Study for the Safety of Efluelda Tetra Pre-filled Syringe.
- 2상모집 예정A Study Exploring the Effect of Adjuvanted RZV or RSVPreF3 Vaccines on Coronary Plaque Progression in Adults >=50 Years of Age at Risk for Cardiovascular Events
- 3상모집 예정Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Infants and Toddlers in China
- 1상모집 예정A Study of V132 in Healthy Older Participants (V132-001)
- 2상모집 예정A Clinical Study of V540A in Healthy Female Participants (V540A-005)
- 4상모집 중Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines
- 1상모집 예정A Clinical Trial to Look at the Safety and Immune Responses of the RNA-based Vaccine BNT168 in Adults Living With or Without HIV
- 1/2상모집 중PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma
- 3상모집 중A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Japanese Healthy Pregnant Women
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